Lofton brings an intercultural identity to his paintings. The artist moved to Mexico in the 1990s and became a part of a small community of artists that included Elizabeth Catlett and Francisco Mora. His work provides a commentary rooted in the black experience while finding a spiritual bond between African and Mexican designs.

Lofton honed his craft from 1948-1954 at the Art Students League and from 1971-72 at the School of Visual Arts in New York City. During that time he became a prolific artist, creating his works in a loft in lower Manhattan. His work has been exhibited extensively in New York City, Florida and Mexico.